A recently published article in the Lancet 2010:375 (9716):743-51 demonstrates that using an artificial pancreas system overnight can reduce nocturnal hypoglycemia in type I DM kids and teens. In fact, the first clinical trial of an artificial pancreas system delivering glucagon and insulin has shown it can prevent development of hypoglycemia.
Dr. Roman Hovorka discusses how closed loop systems might help address the issue of self-management in this diabetic population, as well as challenges in clinical practice in using the system with current insulin therapies and clinical infrastructure.
The complexities around treatment for type I diabetes still requires a comprehensive approach, meaning both device and drug therapies will need to be studied further to optimize successful treatment.
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